Publications

Scientific publications

1. Pancreatic ductal adenocarcinoma ubiquitination profiling reveals specific prognostic and theranostic markers

A El Kaoutari , N A. Fraunhoffer , S Audebert , L Camoin , Y Berthois , O Gayet , J Roques , M Bigonnet , J Ciccolini , J L. Iovanna , N J Dusetti , P Soubeyran

Under reviewing in PNAS journal 2022

2. Menin inhibition suppresses castration-resistant prostate cancer and enhances chemosensitivity

C Cherif, TN Dang, T Khanh Le, N Carbuccia ,P Finetti , A El Kaoutari, J Vernerey, L Fazli ,M Gleave M Manai, D Birnbaum, P Barthélémy, F Bertucci , D Taïeb

Oncogene 2022

3. Metabolomic profiling of pancreatic adenocarcinoma reveals key features driving clinical outcome and drug resistance

A El Kaoutari, N A Fraunhoffer, O Hoare, C Teyssedou, P Soubeyran, O Gayet, J Roques, G Lomberk, R Urrutia, N Dusetti, J Iovanna

EBioMedicine 2021

4. Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease

S Martens, K Coolens, MV Bulck, T Arsenijevic, J Casamitjana, AF Ruiz, A El Kaoutari, JM Villareal, H Madhloum, F Esni, Y Heremans, G Leuckx, H Heimberg, L Bouwens, P Jacquemin, DLD Paep, N D'Haene, C Bouchart, N Dusetti, JL Laethem, W Waelput, P Lefesvre, F Real, M Rovira, I Rooman

Gut 2021

5. A glycosyltransferase gene signature to detect pancreatic ductal adenocarcinoma patients with poor prognosis

YM Abdelhalim, A El Kaoutari, F Silvy, M Rubis, M Bigonnet, J Roques, J Cros, R Nicolle, J Iovanna, N Dusetti, E Mas

EBioMedicine 2021

6. Exploring the Complementarity of Pancreatic Ductal Adenocarcinoma Preclinical Models

O Hoare, N Fraunhoffer, A Elkaoutari, O Gayet, M Bigonnet, J Roques, R Nicolle, C McGuckin, N Forraz, E Sohier, L Tonon, P Wajda, S Boyault, V Attignon, S Tabone-Eglinger, S Barbier, C Mignard, O Duchamp, J Iovanna, N J Dusetti

Cancers 2021

7. Basal-like and Classical cells coexist in pancreatic cancer revealed by single cell analysis on biopsy-derived pancreatic cancer organoids from the classical subtype

N Juiz, A Elkaoutari, Odile Gayet, Martin Bigonnet, Julie Roques, Rémy Nicolle, Juan Iovanna

FASEB Journal 2020

8. Targeting mitochondrial complex i overcomes chemoresistance in high oxphos pancreatic cancer

R Masoud, G Reyes-Castellanos, S Lac, J Garcia, S Dou, L Shintu, N Abdel Hadi, T Gicquel, A El Kaoutari, B Diémé, F Tranchida, L Cormareche, L Borge, O Gayet, E Pasquier, N Dusetti, J Iovanna, A Carrier

Cell Reports Medicine 2020

9. A metagenomics investigation of carbohydrate-active enzymes along the goat and camel intestinal tract

S Al-Masaudi, A El Kaoutari, E Drula, E M Redwan, V Lombard, B Henrissat

International Microbiology 2019

10. Regulation of the positive transcriptional effect of PLZF through a non-canonical EZH2 activity

M Koubi, M Poplineau, J Vernerey, L N’Guyen, G Tiberi, S Garciaz, A El-Kaoutari, M A Maqbool, JC Andrau, C Guillouf, A J Saurin, E Duprez Nucleic Acids Research, 2018

11. Introns protect eukaryotic genomes from transcription-associated genetic instability

Amandine Bonnet, Ana R Grosso, A Elkaoutari, E Coleno, A Presle, S C Sridhara, G Janbon, V Géli, S F de Almeida & Benoit Palancade

Molecular Cell 2017

12. Binding to RNA regulates Set1 function.

Pierre Luciano, J Jeon, Abdessamad El-kaoutari, D Challal, T Candelli, F Jourquin, J Kim, D Libri, Vincent Géli

Cell Discovery 2017

13. JAM-C is a novel biomarker of poor prognosis and identifies rare leukemia-initiating cells with activated Src family kinase pathway in Acute Myeloid Leukemia

M. De Grandis, F. Bardin, C. Fauriat, C. Zemmour, A. El Kaoutari, A. Sergé, S. Granjeaud, L. Pouyet, C. Montersino, S. Chretien, MJ.Mozziconacci, R. Castellano, G. Bidaut, JM. Boher, Y. Collette, S. Mancini, N. Vey1, and M. Aurrand-Lions

Cancer Research. 2017

14. A Metagenomics Investigation of Carbohydrate-Active Enzymes along the Gastrointestinal Tract of Saudi Sheep

Al-Masaudi S, El Kaoutari A, Drula E, Al-Mehdar H, Redwan EM, Lombard V, Henrissat B.

Frontiers in Microbiology. 2017

15. Le microbiote intestinal et la digestion de polysaccharides,

Abdessamad El Kaoutari, Fabrice Armougom, Didier Raoult, Bernard Henrissat

Medecine/Science. 2014

16. Comparative genomics analysis of Lactobacillus species associated with weight gain or weight protection

F Drissi, V Merhej, E Angelakis, A El Kaoutari, F Carrière, B Henrissat, D Raoult

Nutrition & Diabetes. 2014

17. The abundance and variety of carbohydrate-active enzymes in the human gut microbiota

El Kaoutari Abdessamad, Armougom Fabrice, Gordon JI, Raoult Didier, Henrissat Bernard.

Nature Reviews Microbiology. 2013

18. Development and validation of a microarray for the investigation of the CAZymes encoded by the human gut microbiome

Abdessamad El Kaoutari, Fabrice Armougom, Q Leroy, B Vialettes, C Robert, M Million, Didier Raoult, Bernard Henrissat

PLoS One. 2013